KYBELLA® is the first and only FDA-approved injectable drug that contours and improves the appearance of submental fullness, also known as double chin. The active ingredient in KYBELLA® is deoxycholic acid, a naturally occurring molecule in the body that aids in the breakdown and absorption of dietary fat.



What is submental fullness?

Submental fullness, sometimes referred to as “double chin,” is a common, yet undertreated facial aesthetic condition. It can detract from an otherwise balanced and harmonious facial appearance, leading to an older and heavier look.

Submental fullness can impact a broad range of adults, including both women and men, and can be caused by aging, genetics and weight gain.

What is KYBELLA® (deoxycholic acid) injection?

KYBELLA® (deoxycholic acid) injection is the first and only FDA-approved injectable drug that contours and improves the appearance of submental fullness due to submental fat.

KYBELLA® is indicated for improvement in the appearance of moderate to severe convexity or fullness associated with submental fat in adults.

The safe and effective use of KYBELLA® for the treatment of subcutaneous fat outside the submental region has not been established and is not recommended.

What are the side effects with KYBELLA® ?

The safety profile of KYBELLA® is well-characterized. KYBELLA® has been the focus of a global clinical development program involving over 20 clinical studies with more than 2,600 patients worldwide, of which over 1,600 have been treated with KYBELLA® .

The most common adverse reactions were edema/swelling, hematoma/bruising, pain, numbness, erythema and induration.

How many treatments will I need?

You and your health care provider will customize your KYBELLA® treatment regimen, including how many treatments you need, based on your desired chin profile.

Many patients experience visible results in 2 to 4 treatment sessions. During these sessions, your HCP will administer KYBELLA® into the fat under your chin using multiple injections. Up to 6 treatment sessions may be administered spaced no less than one month apart.

How long will the results last?

When injected into the fat under your chin, KYBELLA® causes the destruction of fat cells. Once destroyed, those cells cannot store or accumulate fat. After the aesthetic response is achieved, retreatment with KYBELLA® is not expected.


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